Watercooled ITX gpu's make little sense in a way that if there's space for a separate radiator and who knows what else, then better just use a full sized pgu instead of the whole watercooling scenario. Mini gpu's are mostly used in the smallest cases like Velka 3 and the like.
I would also like to see an Ampere itx gpu and I'm a bit disappointed that this new generation was only focused on performance so much that they did not care too much for power consumption and temperatures. I understand that it's probably easier to make some card powerful like that, but innovation in other areas, like consumption and temps can also be called progress, it should be regarded as a worthy direction to head towards, espeically nowdays. I think that focusing on these departments would be the best for the SFF community, yet currently even the bigger cases struggle with the strange cooling solutions that the 3080 and 3090 FE cards have.
Yet one aftermarket company should realize that the users require mini gpu's are not an insignificant amount, if we take into account that nobody did an Ampere itx card yet. So whoever makes the first product, will totally reap the whole market for themselves! A lot of people with Velka 3, K39, Geeek 30, Lazer3D and who knows what else will make purchase. First company to do it will get all the money. This should be enough motivation for any of them to make one.