I think that if it's clearly not comfortable for a component to be housed in an ITX case despite managing it to work, means that it shouldn't be used. Same reason why I don't find the Asetek 645 a likeable idea here. The 3080 FE falls into this category too. It's quite a looker, but not having it in the Dan A4 is something I can live with.
Of course, still there are some aftermarket options for the 3080 that could be compatible and the upcoming 3070 FE which sounds much more suitable. Not to mention that I still can't buy any ampere cards in this particular spot in Europe, even if I want to, so I'm having a regular 2060 for now. It'll get the job done, while staying cool with low consumption and I'll plan to hold on to it for quite a while, since it'll still prove to be an upgrade and definetly won't be hindering any of my computing tasks or games. From the new gen lineup, I'm more interested in the 3070 than any of the above if it's cooler, quieter and overall more suitable in the Dan A4 and just leave those bigger gpu's for folks with NR200's and the like.