By the second exhaust, you mean the front of the card? I'm curious about how much mini cards will throttle then, because Custom MOD makes metal cases with the same layout that I'm planning but the front of their cases are also lack exhaust vents, like mine. I don't know how hot the cards get with the customers that bought their cases, though.
Adding front vents will require a redesign in a way that I'd be happy with how it will also fit in with the rest of the case. I could offer side panels with more ventilation on the front edge, for example have a wide notch that cuts inwards so air moves out of the edges.
The simplest heat test I could do is just test it with as open a frame as possible, have all the available holes uncovered. You used PLA to print your prototypes, correct? I plan to go straight to ABS for my prototypes, so it should be more heat resistant to GPU and CPU temperatures.
For Flex ATX PSUs, that is more probable in a separate, larger variation of the case. Although I might just settle with SFX.