I've decided I like the hexagonal vent pattern better than the slotted design. The slots are nice when hiding the mounting holes for the radiators, but this design is not going to have vents on either side to keep machine time down and perhaps allow for tempered glass to be used (if possible). At this point however, I think I will be using acrylic panels and will need to find a way to make them easily removable.
I just need to stop sitting on this design and make it. Therefore, I am going to stop trying to get a slim DVD drive mount squeezed in but I am going to make sure I can support a dual-slot PCIe device (or 2 x single-slot).
Therefore, I am going to make the remaining mounting and button holes, create the hexagonal vents, and ensure all fastener clearances are good to go. I am going to try and take a day off this upcoming week (other than Labor Day) and get this design ready for prototyping. Updates are going to come "fast and furious" beginning next week.
I agree, integral DVD drives should be low on the priority list and that the hex vents are nicer. When you say 2-slot, are you thinking anything thicker is a no-go, or will a 2.5 maybe fit?