Short answer is yes, it is very much possible!
You'd likely have to think about making your own frame and enclosure, knowing how the monitor I/O is situated would be beneficial I suppose, all the components ought to have room!
I'm afraid I can't be of much more help here other than that though. but if you start it I'd be glued to your thread on it, been crazy for 34" Ultrawide AIOs since I saw the Origin PC Omni being teased some time ago!