@Necere I chopped up the bottom my V5 this weekend. I wanted my bottom rad in a different position (as far back and close to the open side as possible) and cut new holes to line up with the fans. Assuming we're past the point of changing anything on V6, maybe this makes for some brainstorming material for any future revisions.
The frame still doesn't flex at all, though I do need to be careful about grabbing by the bottom and messing up the rad.
One of my Gentle Typhoons failed, so I'm replacing all of my fans with Noctua NF-A12 (x25 on the side and x15 in the bottom). More pics of this build will go in its own thread when I'm done.