Well, the 3000 series had a large amount of SFF ITX GPUs capping with the 3060ti which was roughly as powerful as a RTX 2080. There is a good chance we will see something in the RTX 3070 to RTX 3080 speed. I haven't heard anything from company reps yet.
There aren't any SFX PSUs with native 16pin but there will be soon.
I have used the Louqe Cobalt cable in my MI-6.
Never got anny "large ammonts" of itx cards where i live And the MSI aeros seemed to take a step back from the awsome1070, with the 3060 ti beeing noisy and no zero fan mode. lets hope someone makes what a great card.
Waiting Corsair to release a 2x8pin to 12VHPWR itx cable for SF600/750. seem to remember optimum tech has a custome cable of sort in his last builds. That silverstone psu seems great, Im sure Corsair and others are working on the new standards to.