I have purchased quite a few computers that use conformal coating on the circuit cards and motherboards. (for HELB/LOCA nuclear applications where a humid environment could be possible) All I/O connectors go through weatherproof seals and mil-spec Amphenol connectors. For the boards, it's a pain in the ass to perform component-level repairs, since the conformal coating needs to be removed and reapplied after for something as simple as replacing a surface mount component. (I recommend taking IPC 7711/7721 training at a minimum if you plan to do so) For our upcoming plant process computer replacement project, I ordered the Neousys Nuvo-5100VTC rugged models for all our workstations -- with i7 6700's, SSD's, and dust seals on all unused ports. (this is for mild control room environments only) It's quite hard to schedule taking equipment out of service for preventative maintenance for cleaning and fan replacement since it needs to stay running for several years straight. I figured fanless and solid state would make a nice upgrade. I'm also powering them via auctioneered external Phoenix DC power supplies, so they can stay running in divisional power outages, or when a UPS needs to be swapped.