Ah, I forgot some USB are off the CPU.
So I guess the SATA like you mentioned and the X370 could potentially do bifurcation are the only differences.
I'm not really sure that there are USB connections from the CPU, I know that it delivers some of its pcie lanes to the chipset (pcie3 x4) and that the chipset does the distribution for ethernet, sata, USB, audio and other stuff
However if we take a look at the X300 and the A300 you can see that there are 4x usb 3.1 gen1 there, but Im not entirely sure its just a passthrough thing or if it needs to make them USB.
Bifurcation is one thing that I truly forgot, but for me the main difference between the chipsets is how many sata you are going to use and that is if you are using nvme (and you should )
But that restriction in itself is of concern for those more high end and expensive offerings of nvme, I can only think samsung and corsair that are using those speeds (im quite sure there are like 300 other devices and companies that use that).
My intel 600p should do quite alright given its speeds.