Plexiglass is just a brand name of Acrylic while Lexan is a brand name of polycarbonate sheeting.
I personally would prefer Acrylic over Lexan because Acrylic is less easily scratched + higher clarity + less yellowing over time. It is relatively better aesthetically, not that Lexan is ugly though.
BTW, I think Sunbeamtech and Geeek (and probably the rest) use Acrylic as their material of choice, probably for the above reasons. And, of course, acrylic is cheaper too.
But, there are other important factors if you are going to DIY your own case. Eg acrylic is more prone to cracking if you drill a hole through it.
Regarding static electricity, I once used an acrylic bench table for several years and I did not come across any related problem. This is just my personal experience.