
AMD just released their RX6600 GPU - with only 130W TDP actually a perfect card for ITX - but it seems ASRock is so far the only partner who offers a card of roughly that size.
The RX 6600 Challenger ITX is designed basically the same like the RX 6600XT version. Street price is estimated to be about USD 130,- cheaper compared to the XT variant, but let's wait and see...
Official product page:

ASRock Radeon RX 6600 Challenger ITX 8GB
<b>Clock: GPU / Memory</b>, Boost Clock: Up to 2491 MHz, Game Clock: Up to 2044 MHz, Base Clock: 1626 MHz<br /><b>Key Specification</b>, 7nm AMD Radeon™ RX 6600 Graphics, 8GB 128-bit GDDR6, AMD RDNA™ 2 Architecture, PCI Express 4.0 Support, 1 x 8-pin Power Connectors, ‧2 x DisplayPort™ 1.4 with...