Toying with layouts for stuff on front. Slim-slot load 5.25" optical drive I'm quite tempted by. 4 USB's might be a bit much though 
I might move the USB's to the other side too, and then put the headphone jack where the USB's currently are.
I'm curious how many headphone/microphone inputs a motherboard can take, it'd be quite nice to have a headphone connector, microphone connector, and combined connector. Would save me ever having to use splitters of any type ever again. I might work on the shape of the grill a bit more, Ii'm beginning to think a bit more rounded might be better... Not sure yet. I also need to position the power button, a little LED power indicator might be quite nice too.
If I do go for a non slim-slot-load optical drive, I'd quite like to be able to mount on a grill or to the front of it like the Bitfenix Neos case does, I'm curious how that case manages to mount it though, and the compatibility of such a system...
**EDIT: Added image for Bitfenix Neos**
It's a far nicer finish then just seeing a boring old CD/DVD drive, my current case even goes to the effort of a little spring-loaded door which opens and closes in sync with the dvd drive, which is obviously another option...
