This cable was released back in 2017. No tweak is needed for Gen 4 up to 50cm. They are tweaking it to run up to 75cm ~ 100cm, and hopefully runs 30cm~ 50cm in Gen 5 next year.
We have tested LINKUP PCIE 3.0 (future 4.0 ready) Twinax (same as 3M technology) riser cable ( 300mm and 500mm )with Gigabyte X570 Gaming X and Sapphire AMD Radeon RX 5700 XT runs at PCIE x16 4.0 with no issue.