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Hello, I just did my first itx build and used the tomahawk mini-itx case. I run 4xcorsair pro 120's. 1 in the front pulling air in, two on bottom pulling air in, 1 rear exhaust and then an nzxt z series AIO on top with those fans exhausting as well. My hard ware is asus X570-i, corsair dominator 32gb 3644 RAM, AMD ryzen 7 3800xt and am rtx 3060ti. Temps stay in a great range with this set up during my benchmarks. I've had no cooling issues. I'd say as long as you have proper air movement through the case the components will be just fine.