It looks like there would be a lot of positive pressure with the config pictured, GPU and AIO sucking in air. How do you plan on venting that? I would suggest vents both top and bottom along with small feet to allow air flow underneath.
I really like the look of this case! I'm currently rocking a Ghost S1 with a top hat to hold a 240 mil AIO but I'm not sold on the aesthetics of the top hat system so this layout is exactly perfect. Looks a bit thinner as well, which is great when you don't require air cooler clearance.
+1 for...