I have a Gigabyte RX 6800 XT, it's quite big, and a Ryzen 5900X with AIO 240mm watercooling. I will look into the H2O, but I don't plan to travel very often, 2-3x a year.
Edit: I looked the gpu restrictions up, the card is 3mm higher (58mm) than the spec sheet of A4-H2O supports (55mm)